Lady Bug is something that seems worthwhile to be seen on MSX... 
........of course they can be played on coleco emulators, just tested Pitstop on Virtual Colecovision, and now it worked.
What I meant was, it´s more fun to get those games "burned" to cartridges to play them on REAL msx, than just use coleco emulator.
That´s why I am waiting cartridge release of Montezuma´s Revenge....
well... ROOT BEER TAPPER is a must for every beer lover! 
You must serve beers to thirsty customers (they have nasty ways to "treat" you if you aren´t fast enough...
) in various bars. Tip: MSX-DEV´06 basic game "Penguin Café" is pretty straightforward clone of ROOT BEER TAPPER. But of course action in (machine-code) TAPPER is more frantic! 
it has excellent graphics too!
PEPPER II is like pacman, but it´s 1.000.000 times more exciting!!!! it has four screens (instead of pacman´s one..) which can be entered at any time, if you go to tunnel in pacman, you just appear to another side of screen, in PEPPER II, "Exits (1-4)" are used to change screen whenever you want!!! So you can decide in which order you want to finish each screen! 
REALLY FUN GAME!!!!
Older role playing freaks may probably remember game called "GATEWAY TO APSHAI", it is real time arcade adventure type role playing game!!! You can slay monsters (many different types) with your sword, use keys, spells, locate traps, etc... if you EVER have wanted fast role playing game, THIS IS A MUST!!!!!!!!!!!! I must confess, that I have never been role playing freak, but I have always liked this game a lot!!!!!!!!!
I also think Pepper II is a very exciting game. Resembles Pac-Man quite much.
Don't forget to mention that, instead of just eating dots, you have to "zip" the blocks closed and you can also unzip 'em by retracing your tracks.
Cool and addictive game!