It would be cool if someone would make this. FINALLY. 
(Oh, and Symbasic is kind of on the way, but what you want is a very optimizing basic compiler, like MSX-BASIC Kun, but then implemented on modern hardware, taking care of all the calculation power you have there!)
Indeed, Symbasic or now days called Unify is already a lot like this. Unify is like a dot.net language and can be compared to VB.NET or C#.NET. You have all the benefit of the modern PC, You can design your screens and convert grapics, you can code in object orientated way and everything is compiled to assembly. Trebmint did a lot of work last months and the compiler is optimized a lot now. Of course it is only for the SymbOS.
It looks like this:
Today as we speak i'm working on a multiuser -chat program (as we only had peer to peer) . I designed a chat server that is on the internet and you simply connect with a client to the server. The MSX version is designed in Unify.
I also desgined a PC version ;)
beside using the unify language, you can switch in your project. Between Assembly and Unify. or use both.
I cannot write a word assembly so that is not for me but i think if you like assembly more you are still able to use it.
Anyway.. i don't want to go off topic but when Unify is released it is maybe worth a try.
